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王一兵

发布者:  时间:2021-09-17 19:28:57  浏览:

 

1.个人基本信息

 王一兵,副教授,主要从事离子通道基因调控运动代谢机制以及基于腺相关病毒AAV基因治疗研究。目前为止,共发表SCI学术文章11, 以第一作者(含共同第一)等身份发表在 Nature Communications (IF2021=14.919, 中科院1区顶刊)MolecularCell (IF2021=17.970, 中科院1区顶刊)等国际知名期刊上4篇。担任Metabolism Open等国际期刊的审稿专家。 

     欢迎感兴趣的研究生和本科生加入。联系方式:wangyibing@sus.edu.cn. 

 

2. 教育和工作经历 

20009-20047         复旦大学化学系  理学学士 

20049-20097         中国科学院上海有机化学研究所  有机化学  理学博士 

20098-200911       中国科学院上海有机化学研究所  研究助理      

201011-201312     美国德州大学西南医学中心UT Southwestern Medical  

                                                   Centerat Dallas生物化学系博士后 

20141-201611       美国德州大学西南医学中心UT Southwestern Medical  

                                                   Centerat Dallas生物化学系博士后 

201612-201712     美国德州大学西南医学中心UT Southwestern Medical  

                                                   Centerat Dallas生物化学系研究科学家 

20181-20211         北京生命科学研究所遗传筛选中心主任  

20211-至今                      上海体育学院教师          

 

3.主要学术成果

(1) Wei, G.; Sun, H.; Dong, K.; Hu, L.; Wang, Q.; Zhuang, Q.; Zhu, Y.; Zhang, X.; Shao,Y.; Tang, H.; Li, Z.; Chen, S.; Lu, J.; Wang, Y.; Gan, X.; Zhong, T.; Gui,D.; Hu, X.; Wang, L.; Liu, J.

Thethermogenic activity of adjacent adipocytes fuels the progression of ccRCC andcompromises anti-tumor therapeutic efficacy. Cell Metab. 2021 Sep8:S1550-4131(21)00375-2. doi: 10.1016/j.cmet.2021.08.012 (IF2021=27.287) 

 

(2)Liang, C#.; Wang, Y#.; Murota, Y.; Liu, X.; Smith, D.; Siomi, M.; Liu,Q*.  (#: co-first authors)      

TAF11assembles the RISC loading complex to enhance RNAi efficiency. Mol. Cell.2015, 59, 807-818 (IF2021=17.970)

 

(3)Wang, Y#.; Cao, L#.; Lee, CY#.; et al Kobayakawa, K.; Beutler, B.; Liu, Q*. (#: co-firstauthors)      

Large-scale forward genetics screening identifies Trpa1 as achemosensor for predator odor-evoked innate fear behaviors. Nat. Commun. 2018, 9, 2041(IF2021=14.919)

 

(4)Egerod, K*.;Petersen, N.; Timshel, P.; Rekling, J.; Wang, Y.; Liu, Q.; Schwartz, T.;Gautron, L*. Profiling of G protein-coupledreceptors in vagal afferents reveals novel gut-to-brain sensing mechanisms. Mol.Metab. 2018, 12, 62-75  (IF2021=7.422)  

 

(5) Leon Mercado, L#.; Caron, A#.; Wang, Y.; Burton, M.;Gautron, L*. (#: co-first authors)   Identification of Leptin receptor-expressing cells in thenodose ganglion of male mice. Endocrinology. 2019, 160, 1307-1322. (IF2021=4.736)

 

(6)  Zheng, S*.; Wang, Y.; Liu, H.; Chang, W.; Xu, Y.; Lin, F*. Prediction of hemolytic toxicity for saponins bymachine-learning methods. Chem. Res. Toxicol. 2019, 32,1014-1026.  (IF2021=3.739)

 

(7)  Zheng, S*.; Wang, Y.; Liu, W.; Chang, W.; Liang, G.; Xu, Y.;Lin, F*. In Silico pprediction of hemolytic toxicity on the human erythrocytesfor small molecules by machine-learning and genetic algorithm. J. Med. Chem.2020, 63, 6499-6512. (IF2021=7.446)

 

(8) Zheng, S*.; Xiong, J.; Wang, Y.; Liang, G.; Xu, Y.; Lin, F*. Quantitative prediction of hemolytic toxicity for smallmolecules and their potential hemolytic fragments by machine learning andrecursive fragmentation methods. J. Chem. Inf. Model. 2020, 60,3231-3245. (IF2021=4.956)

 

(9)Wang, Y.; Zhang, Y.; Zhu, Z.; Zhu, S.; Li, Y.; Li, M.; Yu, B*.Exploration of the correlation between the structure, hemolytic activity, andcytotoxicity of steroid saponins. Bioorg. Med.Chem. 2007,15,2528-2532    (IF2021=3.641) 

 

(10)Wang, Y.; Zhang, Y.; Yu, B*. The cytotoxicity of saponins correlateswith their cellular internalization. ChemMedChem. 2007, 2,288-291     (IF2021=3.466)

 

(11)Li, W.; Qiu, Z.; Wang, Y.; Zhang, Y.; Li, M.; Yu, J.; Zhang, L.; Zhu,Z.; Yu, B*. Synthesis, cytotoxicity, and hemolytic activity of 6'-O-substituteddioscin derivatives. Carbohydr. Res. 2007, 342, 2705-2715 (IF2021=2.104)    

 

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